The 5th edition of the Mediterranean Machine Learning (M2L) summer school will be structured around 5 days of keynotes, lectures and intensive hands-on sessions on the most recent and fast developing core areas of Machine Learning. The intended audience is primarily Doctoral candidates and exceptional Master's and Bachelor's students, academics, professionals, and practitioners worldwide. The school will focus on Natural Language Processing, Ethics and fairness, Computer Vision, Generative Models, Reinforcement Learning and real world applications of Deep Learning. The program includes optional poster sessions and social activities to foster networking.